Bacterial pathogenicity and antibiotic resistance are of concern for environmental safety and public health.Accumulating evidence suggests that wastewater Handset Membrane Cable treatment plants (WWTPs) are as an important sink and source of pathogens and antibiotic resistance genes (ARGs).Virulence genes (encoding virulence factors) are good indic
Bone Marrow Mesenchymal Stem Cells and Electroacupuncture Downregulate the Inhibitor Molecules and Promote the Axonal Regeneration in the Transected Spinal Cord of Rats
Our previous study has reported that electroacupuncture (EA) promotes survival, differentiation of bone marrow mesenchymal stem cells (MSCs), and functional improvement in spinal cord-transected rats.In this study, we further investigated the structural bases of this functional improvement and the potential mechanisms of axonal regeneration in inju
Reduced tyrosine kinase inhibitor dose is predicted to be as effective as standard dose in chronic myeloid leukemia: a simulation study based on phase III trial data
Continuing tyrosine kinase inhibitor (TKI)-mediated targeting of the BCR-ABL1 oncoprotein is the standard therapy for chronic myeloid leukemia (CML) and allows for a sustained disease control in the majority of patients.While therapy cessation for patients appeared as a safe option for about half of those patients with optimal response, no systemat